MTURN

Across TCGA cell cohorts, MTURN RNA expression is significantly associated with the go_rna of many other GO terms, with 4,061 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MTURN-associated GO terms across cancer lineages are Positive regulation of autophagy, Regulation of protein localization to mitochondrion, and Regulation of vacuole organization. Each is linked with MTURN in more than 8 cancer types. Because this analysis shows association rather than direction, both MTURN-to-partner and partner-to-MTURN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of autophagy grouped by MTURN-low versus MTURN-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTURN→partner) and Y-score (partner→MTURN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Positive regulation of autophagy →	+0.057	+0.970	<.001	<.001	3	9
LIVER	Regulation of protein localization to mitochondrion →	+0.082	+0.816	.004	.005	3	8
LUNG_NSCLC_LUAD	Regulation of vacuole organization →	+0.044	+0.725	<.001	.006	3	8
URINARY_TRACT	Epigenetic programing of male pronucleus →	+0.111	+1.372	<.001	<.001	3	8
LUNG_SCLC	G protein-coupled receptor internalization →	-0.210	-1.805	<.001	<.001	3	8
LUNG_NSCLC_LUAD	Regulation of autophagosome assembly →	+0.054	+0.877	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,061 associations by consensus.

Positive regulation of autophagy by MTURN expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →