MTSS2

Across TCGA patient cohorts, MTSS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,421 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MTSS2-associated proteins across cancer lineages are PTK7, DENND2D, and GMPPA. Each is linked with MTSS2 in more than 5 cancer types. Because this analysis shows association rather than direction, both MTSS2-to-partner and partner-to-MTSS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTSS2 versus PTK7 in LSCC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MTSS2→partner) and Y-score (partner→MTSS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PTK7 →	+0.415	+0.484	<.001	<.001	3	6
BRCA	DENND2D →	-0.343	-0.546	<.001	<.001	3	5
LSCC	GMPPA →	-0.404	-0.697	<.001	<.001	3	5
LSCC	GMPPB →	-0.371	-0.684	<.001	<.001	3	5
BRCA	SEPSECS →	-0.290	-0.623	<.001	<.001	3	5
LSCC	ZZEF1 →	-0.240	-0.680	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,421 associations by consensus.

MTSS2 vs PTK7 — LSCC

Explore this scatter interactively →