MTSS2

Across TCGA patient cohorts, MTSS2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,021 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MTSS2-associated genes across cancer lineages are SGIP1, CNRIP1, and EDNRA. Each is linked with MTSS2 in more than 5 cancer types. Because this analysis shows association rather than direction, both MTSS2-to-partner and partner-to-MTSS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTSS2 versus SGIP1 in UCEC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTSS2→partner) and Y-score (partner→MTSS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SGIP1 →	+0.854	+0.400	<.001	.002	3	5
BRCA	CNRIP1 →	+0.689	+0.346	.001	.004	2	6
CCRCC	EDNRA →	+0.905	+0.339	<.001	<.001	3	5
UCEC	DACT1 →	+1.179	+0.550	<.001	<.001	3	5
UCEC	DACT3 →	+0.700	+0.292	<.001	<.001	3	5
GBM	CALM1 →	+0.454	+0.342	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,021 associations by consensus.

MTSS2 vs SGIP1 — UCEC

Explore this scatter interactively →