MTSS2

Across TCGA patient cohorts, MTSS2 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MTSS2-associated genes across cancer lineages are MPP, Class-switched memory B-cells, and Neurons. Each is linked with MTSS2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MTSS2-to-partner and partner-to-MTSS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MPP grouped by MTSS2-low versus MTSS2-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTSS2→partner) and Y-score (partner→MTSS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	MPP →	+0.035	+3.697	.001	.011	3	2
UCEC	Class-switched memory B-cells →	-0.055	-2.415	.017	.003	3	1
UCEC	Neurons →	-0.020	-3.126	.007	.019	3	1
UCEC	Smooth muscle →	+0.142	+3.338	.004	.005	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

MPP by MTSS2 expression — LIHC

Explore this box plot interactively →