MTSS1

Across TCGA pan-cancer cohorts, MTSS1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated MTSS1 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher MTSS1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated MTSS1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and UCEC show a favorable association.

LUAD, LSCC, and UCEC are the cancer types where MTSS1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	II,III,IV	1.000	0.331	.006	11	view →
LSCC	DFS	Tertile	All	0.671	0.895	.015	9	view →
UCEC	DFS	Tertile	III,IV	1.000	0.484	.026	6	view →
PDAC	OS	Median	IV	0.836	0.431	.017	6	view →
GBM	OS	Median	All	0.452	0.611	.045	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

MTSS1–LUAD (OS)

Open the LUAD breakdown →