MTRR

Across TCGA patient cohorts, MTRR protein abundance is significantly associated with the RNA expression of many other genes, with 11,106 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MTRR-associated genes across cancer lineages are MAGI1, ZNF799, and LILRA1. Each is linked with MTRR in more than 3 cancer types. Because this analysis shows association rather than direction, both MTRR-to-partner and partner-to-MTRR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTRR versus MAGI1 in GBM, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTRR→partner) and Y-score (partner→MTRR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MAGI1 →	-0.564	-0.216	<.001	<.001	3	4
OV	ZNF799 →	-0.512	-0.313	.003	.004	3	4
GBM	LILRA1 →	+0.697	+0.300	<.001	<.001	3	3
LSCC	SUDS3 →	-0.571	-0.302	<.001	.004	3	3
GBM	DSE →	+0.750	+0.333	<.001	<.001	3	3
LSCC	NAPSA →	+2.271	+0.272	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,106 associations by consensus.

MTRR vs MAGI1 — GBM

Explore this scatter interactively →