MTRR

Across TCGA cell cohorts, MTRR RNA expression is significantly associated with the RNA expression of many other genes, with 9,579 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible MTRR-associated genes across cancer lineages are FASTKD3, NSUN2, and CCT5. Each is linked with MTRR in more than 18 cancer types. Because this analysis shows association rather than direction, both MTRR-to-partner and partner-to-MTRR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTRR versus FASTKD3 in LUNG_SCLC, with a Pearson correlation of 0.69.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTRR→partner) and Y-score (partner→MTRR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	FASTKD3 →	+1.047	+0.975	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	NSUN2 →	+1.316	+1.311	<.001	<.001	3	19
OESOPHAGUS	CCT5 →	+1.225	+1.166	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	ICE1 →	+1.039	+1.255	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	TENT4A →	+1.140	+1.269	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	OTULIN →	+1.062	+1.187	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,579 associations by consensus.

MTRR vs FASTKD3 — LUNG_SCLC

Explore this scatter interactively →