MTRNR2L6

Across TCGA patient cohorts, MTRNR2L6 mutation is significantly associated with the RNA expression of many other genes, with 365 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MTRNR2L6-associated genes across cancer lineages are LINC01706, RNA5SP410, and C8orf87. Each is linked with MTRNR2L6 in more than 1 cancer types. Because this analysis shows association rather than direction, both MTRNR2L6-to-partner and partner-to-MTRNR2L6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01706 grouped by MTRNR2L6-low versus MTRNR2L6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTRNR2L6→partner) and Y-score (partner→MTRNR2L6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC01706 →	+0.108	+4.621	<.001	.008	3	2
UCEC	RNA5SP410 →	+1.446	+4.374	<.001	.007	3	2
UCEC	C8orf87 →	+0.177	+4.398	.005	.006	3	1
SKCM	GRIK2 →	+1.159	+3.341	.004	.005	3	1
SKCM	PRPF18 →	+0.606	+3.328	.005	.005	3	1
SKCM	CIAO2A →	+0.732	+3.341	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 365 associations by consensus.

LINC01706 by MTRNR2L6 expression — UCEC

Explore this box plot interactively →