MTRNR2L1

Across TCGA patient cohorts, MTRNR2L1 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MTRNR2L1-associated genes across cancer lineages are Neutrophils, Sebocytes, and Endothelial cells. Each is linked with MTRNR2L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MTRNR2L1-to-partner and partner-to-MTRNR2L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neutrophils grouped by MTRNR2L1-low versus MTRNR2L1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTRNR2L1→partner) and Y-score (partner→MTRNR2L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Neutrophils →	+0.019	+2.166	<.001	.021	3	1
UCEC	Sebocytes →	-0.027	-2.967	.043	.036	3	1
UCEC	Endothelial cells →	-0.044	-3.127	.037	.020	1	1
UCEC	Keratinocytes →	-0.015	-3.041	.046	.021	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Neutrophils by MTRNR2L1 expression — UCEC

Explore this box plot interactively →