MTRF1L

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MTRF1L protein abundance is significantly associated with the RNA expression of many other genes, with 2,982 significant associations in total. COAD shows the largest number of these associations.

The most reproducible MTRF1L-associated genes across cancer lineages are TNK2, SLC25A14, and CRISPLD2. Each is linked with MTRF1L in more than 1 cancer types. Because this analysis shows association rather than direction, both MTRF1L-to-partner and partner-to-MTRF1L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTRF1L versus TNK2 in OV, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTRF1L→partner) and Y-score (partner→MTRF1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVTNK2 →-1.204-0.662<.001<.00132
OVSLC25A14 →-0.516-0.508.005.00232
OVCRISPLD2 →-1.727-0.526.003<.00132
OVTNS2 →-0.990-0.390.003.00732
OVPHF1 →-0.587-0.477<.001<.00132
OVSENP5 →-0.852-0.529.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,982 associations by consensus.

MTRF1L vs TNK2 — OV

Per-sample scatter of MTRF1L vs TNK2 in OV (Pearson r = -0.47).

Explore this scatter interactively →

Exploration