MTRF1

Across TCGA patient cohorts, MTRF1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,538 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MTRF1-associated proteins across cancer lineages are ZMYM2, PDS5B, and TDRD3. Each is linked with MTRF1 in more than 5 cancer types. Because this analysis shows association rather than direction, both MTRF1-to-partner and partner-to-MTRF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTRF1 versus ZMYM2 in GBM, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MTRF1→partner) and Y-score (partner→MTRF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ZMYM2 →	+0.329	+0.322	<.001	<.001	3	6
OV	PDS5B →	+0.297	+0.471	<.001	.003	3	6
BRCA	TDRD3 →	+0.248	+0.477	.001	<.001	3	6
GBM	DIS3 →	+0.330	+0.408	<.001	<.001	3	6
LSCC	GPALPP1 →	+0.361	+0.499	<.001	<.001	3	6
GBM	INTS6 →	+0.254	+0.350	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,538 associations by consensus.

MTRF1 vs ZMYM2 — GBM

Explore this scatter interactively →