MTR

Across TCGA patient cohorts, MTR RNA expression is significantly associated with the protein abundance of many other proteins, with 19,432 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MTR-associated proteins across cancer lineages are RO60, AIDA, and PRUNE1. Each is linked with MTR in more than 7 cancer types. Because this analysis shows association rather than direction, both MTR-to-partner and partner-to-MTR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTR versus RO60 in HNSC, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MTR→partner) and Y-score (partner→MTR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RO60 →	+0.247	+0.576	<.001	.005	3	8
BRCA	AIDA →	+0.301	+0.527	<.001	.001	3	6
LSCC	PRUNE1 →	+0.368	+0.318	<.001	<.001	3	5
PDAC	RPL26 →	-0.550	-0.295	<.001	.002	3	5
BRCA	RPL6 →	-0.486	-0.612	<.001	<.001	3	5
UCEC	SLC3A2 →	-0.557	-0.421	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,432 associations by consensus.

MTR vs RO60 — HNSC

Explore this scatter interactively →