MTR

Across TCGA patient cohorts, MTR protein abundance is significantly associated with the RNA expression of many other genes, with 14,450 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible MTR-associated genes across cancer lineages are ABI3BP, BNC2, and PODN. Each is linked with MTR in more than 7 cancer types. Because this analysis shows association rather than direction, both MTR-to-partner and partner-to-MTR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTR versus ABI3BP in UCEC, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTR→partner) and Y-score (partner→MTR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ABI3BP →	+1.266	+0.338	.001	<.001	3	8
UCEC	BNC2 →	+0.883	+0.263	<.001	<.001	3	7
UCEC	PODN →	+1.352	+0.351	<.001	.001	3	7
BRCA	LRRN4CL →	+1.060	+0.250	<.001	<.001	3	7
UCEC	CHRDL1 →	+1.553	+0.244	<.001	<.001	3	7
UCEC	PTGFR →	+1.475	+0.424	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,450 associations by consensus.

MTR vs ABI3BP — UCEC

Explore this scatter interactively →