MTPAP

Across TCGA cell cohorts, MTPAP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,370 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MTPAP-associated GO terms across cancer lineages are Mitochondrial RNA 3'-end processing, Mitochondrial RNA processing, and Nuclear pore complex assembly. Each is linked with MTPAP in more than 17 cancer types. Because this analysis shows association rather than direction, both MTPAP-to-partner and partner-to-MTPAP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial RNA 3'-end processing grouped by MTPAP-low versus MTPAP-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTPAP→partner) and Y-score (partner→MTPAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Mitochondrial RNA 3'-end processing →	+0.155	+0.881	<.001	<.001	3	18
LIVER	Mitochondrial RNA processing →	+0.101	+0.714	.003	.004	3	15
BREAST	Nuclear pore complex assembly →	+0.132	+0.797	<.001	.002	3	14
LARGE_INTESTINE	Double-strand break repair →	+0.053	+0.621	<.001	<.001	3	14
OVARY	Mitochondrial RNA metabolic process →	+0.077	+0.811	<.001	.001	3	14
BONE	RNA 3'-end processing →	+0.093	+0.723	.001	.004	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,370 associations by consensus.

Mitochondrial RNA 3'-end processing by MTPAP expression — STOMACH

Explore this box plot interactively →