MTPAP

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MTPAP protein abundance is significantly associated with the RNA expression of many other genes, with 5,945 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible MTPAP-associated genes across cancer lineages are P4HA2, FRMD6, and ITGA5. Each is linked with MTPAP in more than 11 cancer types. Because this analysis shows association rather than direction, both MTPAP-to-partner and partner-to-MTPAP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTPAP versus P4HA2 in BONE, with a Pearson correlation of 0.93.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTPAP→partner) and Y-score (partner→MTPAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONEP4HA2 →+4.727+5.212<.001<.001312
LUNG_NSCLC_LUSCFRMD6 →+3.707+2.359.007.008310
LIVERITGA5 →+3.257+2.847<.001.001310
OESOPHAGUSPDLIM4 →+4.041+1.300<.001.001310
BREASTGPX8 →+2.456+1.256<.001<.00139
LIVERTXNDC15 →+1.204+2.273.005.001210
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,945 associations by consensus.

MTPAP vs P4HA2 — BONE

Per-sample scatter of MTPAP vs P4HA2 in BONE (Pearson r = 0.93).

Explore this scatter interactively →

Exploration