Across TCGA patient cohorts, MTOR protein abundance is significantly associated with the protein abundance of many other proteins, with 13,759 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible MTOR-associated proteins across cancer lineages are RICTOR, RPTOR, and RUSF1. Each is linked with MTOR in more than 6 cancer types. Because this analysis shows association rather than direction, both MTOR-to-partner and partner-to-MTOR results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MTOR→partner) and Y-score (partner→MTOR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RICTOR →	+0.207	+0.109	<.001	<.001	3	7
BRCA	RPTOR →	+0.307	+0.218	<.001	<.001	3	6
BRCA	RUSF1 →	+0.691	+0.315	<.001	<.001	3	6
OV	UBE4B →	+0.346	+0.231	<.001	<.001	3	6
BRCA	MFN2 →	+0.319	+0.242	<.001	<.001	2	6
PDAC	MTCH1 →	+0.458	+0.280	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,759 associations by consensus.

Exploration

MTOR survival (RNA) · tumor vs normal (RNA) · all MTOR data types