Across TCGA cell cohorts, MTOR RNA expression is significantly associated with the go_rna of many other GO terms, with 4,726 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MTOR-associated GO terms across cancer lineages are Cellular response to methionine, Response to methionine, and Regulation of transcription of nucleolar large rRNA by RNA polymerase I. Each is linked with MTOR in more than 18 cancer types. Because this analysis shows association rather than direction, both MTOR-to-partner and partner-to-MTOR results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTOR→partner) and Y-score (partner→MTOR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Cellular response to methionine →	+0.122	+1.044	.002	.003	3	19
LUNG_NSCLC_LUSC	Response to methionine →	+0.122	+1.044	.002	.003	3	19
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.155	+0.728	<.001	<.001	3	18
BONE	Regulation of telomerase RNA localization to Cajal body →	+0.116	+0.860	<.001	<.001	3	18
LUNG_NSCLC_LUSC	T-helper 1 cell lineage commitment →	+0.186	+0.810	<.001	<.001	3	18
BLOOD_Myeloma	Replication fork processing →	+0.101	+0.692	<.001	.002	2	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,726 associations by consensus.

Exploration

MTOR survival (RNA) · tumor vs normal (RNA) · all MTOR data types