MTNR1B

Across TCGA cell cohorts, MTNR1B RNA expression is significantly associated with the RNA expression of many other genes, with 1,094 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible MTNR1B-associated genes across cancer lineages are ADAM29, MAGEE2, and TCP10L2. Each is linked with MTNR1B in more than 3 cancer types. Because this analysis shows association rather than direction, both MTNR1B-to-partner and partner-to-MTNR1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTNR1B versus ADAM29 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.72.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTNR1B→partner) and Y-score (partner→MTNR1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	ADAM29 →	+0.114	+0.028	<.001	<.001	3	4
LUNG_NSCLC_LUSC	MAGEE2 →	+0.068	+0.049	<.001	.002	3	4
LUNG_NSCLC_LUSC	TCP10L2 →	+0.044	+0.051	.009	.003	3	3
UPPER_AERODIGESTIVE_TRACT	OR56B1 →	+0.055	+0.023	.006	<.001	3	3
LUNG_NSCLC_LUSC	NLRP9 →	+0.063	+0.049	.004	.005	3	3
LUNG_NSCLC_LUSC	LRRC10 →	+0.022	+0.049	.004	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,094 associations by consensus.

MTNR1B vs ADAM29 — UPPER_AERODIGESTIVE_TRACT

Explore this scatter interactively →