MTND6P22

Across TCGA patient cohorts, MTND6P22 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,052 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MTND6P22-associated GO terms across cancer lineages are Mitochondrial electron transport, NADH to ubiquinone, Aerobic respiration, and Proton motive force-driven ATP synthesis. Each is linked with MTND6P22 in more than 16 cancer types. Because this analysis shows association rather than direction, both MTND6P22-to-partner and partner-to-MTND6P22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial electron transport, NADH to ubiquinone grouped by MTND6P22-low versus MTND6P22-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTND6P22→partner) and Y-score (partner→MTND6P22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Mitochondrial electron transport, NADH to ubiquinone →	+0.049	+0.985	<.001	<.001	1	17
STAD	Aerobic respiration →	+0.034	+0.530	<.001	<.001	3	15
STAD	Proton motive force-driven ATP synthesis →	+0.049	+0.656	<.001	<.001	3	13
STAD	Respiratory electron transport chain →	+0.040	+0.653	<.001	<.001	3	13
ESCA	Proton transmembrane transport →	+0.034	+0.847	<.001	<.001	1	14
ESCA	Oxidative phosphorylation →	+0.042	+0.955	<.001	<.001	1	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,052 associations by consensus.

Mitochondrial electron transport, NADH to ubiquinone by MTND6P22 expression — ESCA

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