Across TCGA pan-cancer cohorts, MTND6P18 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of MTND6P18’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where MTND6P18 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MTND6P18 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

HNSC, THCA, and STAD are the cancer types where MTND6P18 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTND6P18 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.033	.011	6	view →
THCA	Male	IV	−0.146	<.001	3	view →
STAD	All	All	+0.110	.019	2	view →
BRCA	Female	All	+0.093	.042	2	view →
LIHC	All	All	+0.008	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: MTND6P18 RNA expression & survival · all MTND6P18 data types