MTND5P5

Across TCGA pan-cancer cohorts, MTND5P5 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated MTND5P5 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher MTND5P5 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MTND5P5 expression acts as an unfavorable survival marker, although some lineages such as LUAD and ESCA show a favorable association.

KICH, ACC, and KIRP are the cancer types where MTND5P5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
ACC	OS	Tertile	III,IV	0.145	0.766	<.001	63	view →
KIRP	OS	Tertile	II,III,IV	0.148	0.771	<.001	60	view →
LUAD	DFS	Tertile	III,IV	1.000	0.246	.007	39	view →
PCPG	OS	Tertile	All	0.078	0.955	<.001	27	view →
ESCA	DFS	Tertile	III,IV	0.571	0.261	.012	21	view →
CESC	DFS	Tertile	All	0.582	0.829	.002	18	view →
LGG	OS	Tertile	All	0.182	0.909	<.001	18	view →
PAAD	OS	Tertile	All	0.138	0.590	<.001	18	view →
OV	DFS	Tertile	IV	0.146	0.482	<.001	18	view →
UCEC	DFS	Tertile	II,III,IV	0.092	0.513	.019	18	view →
SARC	OS	Tertile	All	0.210	0.831	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

MTND5P5–KICH (DFS)

Open the KICH breakdown →