Across TCGA pan-cancer cohorts, MTND5P40 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of MTND5P40’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where MTND5P40 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MTND5P40 is over-expressed in tumor.
BRCA are the cancer types where MTND5P40 tumor–normal differential expression is most reproducible.