Across TCGA pan-cancer cohorts, MTND5P30 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of MTND5P30’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where MTND5P30 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MTND5P30 is over-expressed in tumor.
LUSC are the cancer types where MTND5P30 tumor–normal differential expression is most reproducible.