Across TCGA pan-cancer cohorts, MTND5P25 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated MTND5P25 data layer.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MTND5P25 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MTND5P25 expression acts as an unfavorable survival marker, although some lineages such as LUAD and BRCA show a favorable association.
KIRC, LUAD, and BRCA are the cancer types where MTND5P25 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.