MTND5P23

Across TCGA pan-cancer cohorts, MTND5P23 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated MTND5P23 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher MTND5P23 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MTND5P23 expression acts as an unfavorable survival marker, although some lineages such as HNSC and OV show a favorable association.

THCA, KIRC, and SKCM are the cancer types where MTND5P23 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Tertile	II,III,IV	0.276	0.746	<.001	72	view →
KIRC	DFS	Tertile	III,IV	0.167	0.482	.004	48	view →
SKCM	DFS	Tertile	All	0.044	0.766	<.001	45	view →
BLCA	OS	Tertile	IV	0.051	0.600	<.001	36	view →
HNSC	DFS	Tertile	All	0.743	0.303	.020	30	view →
PAAD	OS	Tertile	All	0.274	0.603	.002	27	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	27	view →
UCS	DFS	Tertile	All	0.136	0.523	.034	18	view →
GBM	DFS	Tertile	All	0.143	0.315	.019	9	view →
STAD	DFS	Tertile	IV	0.083	0.366	.004	6	view →
OV	OS	Tertile	IV	0.740	0.551	.032	4	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

MTND5P23–THCA (DFS)

Open the THCA breakdown →