MTND5P22

Across TCGA patient cohorts, MTND5P22 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,795 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MTND5P22-associated GO terms across cancer lineages are Regulation of ubiquitin-dependent protein catabolic process, Regulation of DNA biosynthetic process, and DNA-templated transcription initiation. Each is linked with MTND5P22 in more than 4 cancer types. Because this analysis shows association rather than direction, both MTND5P22-to-partner and partner-to-MTND5P22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of ubiquitin-dependent protein catabolic process grouped by MTND5P22-low versus MTND5P22-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTND5P22→partner) and Y-score (partner→MTND5P22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of ubiquitin-dependent protein catabolic process →	+0.109	+0.133	<.001	<.001	3	4
STAD	Regulation of DNA biosynthetic process →	+0.101	+0.122	<.001	<.001	3	4
STAD	DNA-templated transcription initiation →	+0.107	+0.130	<.001	<.001	3	4
STAD	Telomere maintenance →	+0.103	+0.137	<.001	<.001	3	4
STAD	Regulation of binding →	+0.102	+0.129	<.001	<.001	3	4
STAD	Regulation of DNA binding →	+0.088	+0.130	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,795 associations by consensus.

Regulation of ubiquitin-dependent protein catabolic process by MTND5P22 expression — STAD

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