MTND5P21

Across TCGA pan-cancer cohorts, MTND5P21 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated MTND5P21 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher MTND5P21 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MTND5P21 expression acts as an unfavorable survival marker, although some lineages such as OV and STAD show a favorable association.

UCEC, KICH, and THYM are the cancer types where MTND5P21 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	III,IV	0.636	0.850	.002	126	view →
KICH	DFS	Tertile	II,III,IV	0.043	0.950	<.001	72	view →
THYM	DFS	Tertile	All	0.727	0.921	<.001	45	view →
LIHC	OS	Tertile	All	0.407	0.698	.012	45	view →
OV	OS	Tertile	III,IV	0.438	0.299	.017	42	view →
PAAD	OS	Tertile	All	0.159	0.595	<.001	36	view →
SKCM	OS	Tertile	IV	0.179	0.755	<.001	18	view →
STAD	OS	Tertile	IV	0.805	0.283	.031	18	view →
KIRC	OS	Tertile	All	0.455	0.653	.024	12	view →
ESCA	OS	Quartile	II,III,IV	0.713	0.452	.022	10	view →
THCA	OS	Tertile	III,IV	0.723	0.887	.023	9	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

MTND5P21–UCEC (OS)

Open the UCEC breakdown →