Q-omics provides the consensus-scored MTND5P1 profile across patient tissues and cancer cell-line models. MTND5P1 expression is associated with patient survival in 25 of 34 cancer types, with the highest sampling consensus in UCEC. Among the 18 cancer types available for tumor–normal comparison, MTND5P1 is differentially expressed in 10, with the highest sampling consensus in BLCA. Additionally, MTND5P1 RNA expression shows 16,436 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight UCEC, BLCA, and THYM as cancer lineages where MTND5P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MTND5P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MTND5P1 survival associations across molecular data types. MTND5P1 RNA expression shows survival associations in the most cancer types (25). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MTND5P1 RNA expression–survival associations across cancer types. High MTND5P1 expression shows unfavorable associations in UCEC and KIRC, but favorable associations in LIHC, HNSC, UCS and LGG. The UCEC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .002). Together, the overview and detailed table identify UCEC as the clearest survival context for MTND5P1 RNA expression.
This table summarizes MTND5P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in BLCA for RNA.
This table ranks reproducible tumor–normal expression differences for MTND5P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MTND5P1 shows lower tumor expression in BLCA, STAD, UCEC, BRCA, THCA and COAD. The BLCA box plot shows higher MTND5P1 RNA expression in normal versus tumor tissue (log2 FC = −0.955, t-test p < 0.001).
This table shows molecular features associated with MTND5P1 in patient tissues and cancer cell lines. In patient samples, MTND5P1 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
