Q-omics provides the consensus-scored MTND4P4 profile across patient tissues and cancer cell-line models. MTND4P4 expression is associated with patient survival in 11 of 34 cancer types, with the highest sampling consensus in COAD. Among the 18 cancer types available for tumor–normal comparison, MTND4P4 is differentially expressed in 1, with the highest sampling consensus in KIRC. Additionally, MTND4P4 RNA expression shows 8,107 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight COAD, KIRC, and TGCT as cancer lineages where MTND4P4 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MTND4P4 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MTND4P4 survival associations across molecular data types. MTND4P4 RNA expression shows survival associations in the most cancer types (11). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MTND4P4 RNA expression–survival associations across cancer types. High MTND4P4 expression shows unfavorable associations in COAD, KICH, BLCA and LIHC, but favorable associations in MESO and OV. The COAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify COAD as the clearest survival context for MTND4P4 RNA expression.
This table summarizes MTND4P4 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for MTND4P4. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MTND4P4 shows lower tumor expression in KIRC. The KIRC box plot shows higher MTND4P4 RNA expression in normal versus tumor tissue (log2 FC = −0.005, t-test p = .043).
This table shows molecular features associated with MTND4P4 in patient tissues and cancer cell lines. In patient samples, MTND4P4 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
