MTND4P35

Across TCGA pan-cancer cohorts, MTND4P35 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated MTND4P35 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher MTND4P35 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated MTND4P35 expression acts as an unfavorable survival marker, although some lineages such as KIRP and ACC show a favorable association.

KIRP, ACC, and CESC are the cancer types where MTND4P35 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Median	II,III,IV	0.824	0.522	.001	76	view →
ACC	OS	Tertile	II,III,IV	1.000	0.649	<.001	57	view →
CESC	OS	Tertile	II,III,IV	0.870	0.573	.001	44	view →
DLBC	DFS	Median	All	0.579	1.000	.007	43	view →
THYM	DFS	Quartile	II,III,IV	0.466	0.909	.001	39	view →
UCS	DFS	Tertile	All	0.302	0.718	<.001	36	view →
CHOL	DFS	Median	II,III,IV	0.101	0.571	.001	28	view →
KICH	DFS	Tertile	II,III,IV	1.000	0.533	.023	25	view →
BLCA	DFS	Quartile	II,III,IV	0.479	0.259	.005	23	view →
PAAD	OS	Median	All	0.707	0.367	<.001	23	view →
LUSC	OS	Tertile	II,III,IV	0.494	0.294	.008	23	view →
SKCM	DFS	Tertile	All	0.155	0.256	.005	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

MTND4P35–KIRP (DFS)

Open the KIRP breakdown →