Across TCGA pan-cancer cohorts, MTND4P29 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MTND4P29’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MTND4P29 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MTND4P29 is over-expressed in tumor.
KIRC and THCA are the cancer types where MTND4P29 tumor–normal differential expression is most reproducible.