MTND4P27

Across TCGA pan-cancer cohorts, MTND4P27 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated MTND4P27 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher MTND4P27 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MTND4P27 expression acts as an unfavorable survival marker, although some lineages such as LAML and GBM show a favorable association.

UVM, READ, and LUAD are the cancer types where MTND4P27 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	All	0.126	0.768	<.001	54	view →
READ	DFS	Tertile	All	0.540	0.877	<.001	48	view →
LUAD	OS	Tertile	II,III,IV	0.249	0.595	.009	36	view →
LAML	DFS	Quartile	All	0.702	0.481	.008	36	view →
KIRC	DFS	Tertile	III,IV	0.305	0.650	.021	18	view →
ESCA	OS	Tertile	III,IV	0.387	0.612	.036	15	view →
STAD	OS	Tertile	IV	0.276	0.615	.042	12	view →
THYM	DFS	Tertile	III,IV	0.205	0.774	.007	9	view →
GBM	OS	Tertile	All	0.781	0.374	.048	3	view →
LUSC	DFS	Tertile	All	0.210	0.393	.036	3	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

MTND4P27–UVM (DFS)

Open the UVM breakdown →