Q-omics provides the consensus-scored MTND4P26 profile across patient tissues and cancer cell-line models. MTND4P26 expression is associated with patient survival in 17 of 34 cancer types, with the highest sampling consensus in HNSC. Among the 18 cancer types available for tumor–normal comparison, MTND4P26 is differentially expressed in 9, with the highest sampling consensus in STAD. Additionally, MTND4P26 RNA expression shows 17,129 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight HNSC, STAD, and THYM as cancer lineages where MTND4P26 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MTND4P26 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MTND4P26 survival associations across molecular data types. MTND4P26 RNA expression shows survival associations in the most cancer types (17). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MTND4P26 RNA expression–survival associations across cancer types. High MTND4P26 expression shows unfavorable associations in LGG, KIRC, COAD and ACC, but favorable associations in HNSC and UCS. The HNSC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify HNSC as the clearest survival context for MTND4P26 RNA expression.
This table summarizes MTND4P26 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 9. The strongest signals are observed in STAD for RNA.
This table ranks reproducible tumor–normal expression differences for MTND4P26. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MTND4P26 shows lower tumor expression in BRCA and higher tumor expression in STAD, COAD, HNSC, CHOL and KIRC. The STAD box plot shows higher MTND4P26 RNA expression in tumor versus normal tissue (log2 FC = +0.472, t-test p < 0.001).
This table shows molecular features associated with MTND4P26 in patient tissues and cancer cell lines. In patient samples, MTND4P26 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
