Q-omics provides the consensus-scored MTND4P25 profile across patient tissues and cancer cell-line models. MTND4P25 expression is associated with patient survival in 6 of 34 cancer types, with the highest sampling consensus in COAD. Additionally, MTND4P25 RNA expression shows 5,010 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight COAD, and STAD as cancer lineages where MTND4P25 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes MTND4P25 survival associations across molecular data types. MTND4P25 RNA expression shows survival associations in the most cancer types (6). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

MTND4P25 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	6	COAD (45)	view →

This table ranks reproducible MTND4P25 RNA expression–survival associations across cancer types. High MTND4P25 expression shows unfavorable associations in COAD, UCEC, DLBC, HNSC and THCA, but favorable associations in ESCA. The COAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .005). Together, the overview and detailed table identify COAD as the clearest survival context for MTND4P25 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	All	0.183	0.806	.005	45	view →
UCEC	OS	Tertile	IV	0.066	0.755	<.001	36	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	36	view →
HNSC	OS	Tertile	All	0.239	0.688	.001	27	view →
ESCA	DFS	Tertile	II,III,IV	1.000	0.328	.029	15	view →
THCA	OS	Tertile	All	0.974	0.993	.006	9	view →

Pink = unfavorable, green = favorable. all 6 lineages →

MTND4P25-COAD (OS)

Kaplan–Meier survival curve for MTND4P25 RNA expression in COAD: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with MTND4P25 in patient tissues and cancer cell lines. In patient samples, MTND4P25 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	5,010	STAD (4901)	view →
RNA	4,692	UCEC (2084)	view →