Across TCGA pan-cancer cohorts, MTND4P2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MTND4P2’s most consistent transcriptional readouts.
The strongest signal is observed in bladder urothelial carcinoma (BLCA), where MTND4P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MTND4P2 is over-expressed in tumor.
BLCA and ESCA are the cancer types where MTND4P2 tumor–normal differential expression is most reproducible.