MTND4P14

Across TCGA pan-cancer cohorts, MTND4P14 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated MTND4P14 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher MTND4P14 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MTND4P14 expression acts as an unfavorable survival marker, although some lineages such as COAD and HNSC show a favorable association.

UVM, LUSC, and CHOL are the cancer types where MTND4P14 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.291	0.631	.001	48	view →
LUSC	OS	Tertile	IV	0.001	0.673	.014	36	view →
CHOL	OS	Tertile	All	0.303	0.700	.016	33	view →
COAD	DFS	Tertile	III,IV	0.684	0.300	.017	22	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	21	view →
READ	OS	Quartile	II,III,IV	0.802	0.955	.022	19	view →
HNSC	DFS	Quartile	All	0.793	0.677	.006	11	view →
PRAD	DFS	Quartile	All	0.960	0.866	.009	10	view →
KICH	DFS	Tertile	IV	0.269	0.784	.045	9	view →
STAD	DFS	Tertile	IV	0.219	0.700	.016	6	view →
CESC	OS	Median	All	0.871	0.752	.014	6	view →
DLBC	OS	Quartile	III,IV	0.052	1.000	.045	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

MTND4P14–UVM (OS)

Open the UVM breakdown →