MTND4LP5

Across TCGA pan-cancer cohorts, MTND4LP5 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MTND4LP5’s most consistent transcriptional readouts.

The strongest signal is observed in esophageal carcinoma (ESCA), where MTND4LP5 RNA is repressed in tumor relative to normal tissue. In most cancer types MTND4LP5 is over-expressed in tumor, although a few such as ESCA and KIRC show the opposite, repressed pattern.

ESCA and KIRC are the cancer types where MTND4LP5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTND4LP5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
ESCA	Female	All	−1.023	.023	2	view →
KIRC	All	All	−0.075	.029	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

MTND4LP5–ESCA

Open the ESCA breakdown →