MTND4LP31

Across TCGA pan-cancer cohorts, MTND4LP31 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated MTND4LP31 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher MTND4LP31 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MTND4LP31 expression acts as an unfavorable survival marker, although some lineages such as LUSC show a favorable association.

CESC, KIRC, and STAD are the cancer types where MTND4LP31 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Tertile	All	0.080	0.543	.019	36	view →
KIRC	OS	Tertile	All	0.812	0.882	.009	36	view →
STAD	OS	Tertile	IV	0.099	0.564	.006	18	view →
UVM	OS	Tertile	All	0.290	0.612	.036	18	view →
SARC	DFS	Tertile	All	0.167	0.597	.021	18	view →
UCS	DFS	Tertile	All	0.136	0.523	.034	18	view →
UCEC	OS	Tertile	III,IV	0.616	0.833	.018	18	view →
LUSC	DFS	Tertile	All	1.000	0.388	.034	12	view →
SKCM	OS	Tertile	III,IV	0.358	0.727	.030	9	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

MTND4LP31–CESC (DFS)

Open the CESC breakdown →