MTND4LP3

Across TCGA pan-cancer cohorts, MTND4LP3 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated MTND4LP3 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher MTND4LP3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MTND4LP3 expression acts as an unfavorable survival marker.

UCS, THCA, and BLCA are the cancer types where MTND4LP3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Tertile	All	0.007	0.689	<.001	72	view →
THCA	DFS	Tertile	All	0.141	0.820	<.001	48	view →
BLCA	DFS	Tertile	All	0.198	0.521	.028	45	view →
STAD	DFS	Tertile	IV	0.068	0.480	<.001	36	view →
ESCA	OS	Tertile	All	0.198	0.872	.003	36	view →
LUSC	OS	Tertile	III,IV	0.147	0.664	.028	36	view →
BRCA	OS	Tertile	III,IV	0.111	0.544	.032	18	view →
KIRC	DFS	Tertile	IV	0.221	0.603	.046	18	view →
GBM	OS	Tertile	All	0.174	0.416	.014	9	view →
SKCM	DFS	Tertile	II,III,IV	0.245	0.685	.019	9	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

MTND4LP3–UCS (OS)

Open the UCS breakdown →