MTND4LP26

Across TCGA pan-cancer cohorts, MTND4LP26 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated MTND4LP26 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher MTND4LP26 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MTND4LP26 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

HNSC, KIRP, and STAD are the cancer types where MTND4LP26 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.208	0.698	<.001	171	view →
KIRP	OS	Tertile	II,III,IV	0.161	0.771	.002	81	view →
STAD	OS	Tertile	II,III,IV	0.430	0.734	.006	18	view →
LIHC	DFS	Tertile	III,IV	0.143	0.374	.009	18	view →
PRAD	OS	Tertile	All	0.563	0.883	<.001	18	view →
UCEC	DFS	Tertile	All	0.177	0.653	.007	12	view →
LUAD	OS	Tertile	All	1.000	0.342	.026	9	view →
BRCA	DFS	Tertile	All	0.396	0.534	.026	6	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

MTND4LP26–HNSC (DFS)

Open the HNSC breakdown →