MTND4LP22

Across TCGA pan-cancer cohorts, MTND4LP22 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated MTND4LP22 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher MTND4LP22 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MTND4LP22 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

UCS, DLBC, and HNSC are the cancer types where MTND4LP22 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Tertile	All	0.001	0.690	<.001	108	view →
DLBC	OS	Tertile	All	0.335	0.923	<.001	99	view →
HNSC	OS	Tertile	II,III,IV	0.142	0.675	<.001	81	view →
BLCA	OS	Tertile	All	0.141	0.687	.003	54	view →
PAAD	OS	Tertile	All	0.220	0.468	.039	18	view →
LAML	DFS	Quartile	All	0.154	0.439	.001	18	view →
LGG	OS	Tertile	All	0.758	0.898	.015	15	view →
UCEC	DFS	Tertile	III,IV	0.249	0.602	.042	12	view →
GBM	DFS	Tertile	All	0.048	0.242	.006	9	view →
THYM	DFS	Tertile	All	0.611	0.918	.027	9	view →
STAD	OS	Quartile	IV	0.109	0.576	.007	9	view →
SKCM	DFS	Tertile	All	0.505	0.199	.026	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

MTND4LP22–UCS (OS)

Open the UCS breakdown →