Q-omics provides the consensus-scored MTND4LP16 profile across patient tissues and cancer cell-line models. MTND4LP16 expression is associated with patient survival in 7 of 34 cancer types, with the highest sampling consensus in ESCA. Additionally, MTND4LP16 RNA expression shows 6,758 significant gene co-expression associations, with the highest sampling consensus in COAD. Together, these results highlight ESCA, and COAD as cancer lineages where MTND4LP16 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes MTND4LP16 survival associations across molecular data types. MTND4LP16 RNA expression shows survival associations in the most cancer types (7). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

MTND4LP16 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	7	ESCA (66)	view →

This table ranks reproducible MTND4LP16 RNA expression–survival associations across cancer types. High MTND4LP16 expression shows unfavorable associations in ESCA, LGG, SKCM, KIRP, LUAD and OV. The ESCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify ESCA as the clearest survival context for MTND4LP16 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Tertile	All	0.462	0.731	.001	66	view →
LGG	DFS	Tertile	All	0.388	0.770	<.001	24	view →
SKCM	DFS	Tertile	IV	0.016	0.454	<.001	18	view →
KIRP	OS	Tertile	All	0.608	0.903	.029	18	view →
LUAD	OS	Tertile	III,IV	0.153	0.690	<.001	18	view →
OV	DFS	Tertile	II,III,IV	0.334	0.544	.048	12	view →

Pink = unfavorable, green = favorable. all 7 lineages →

MTND4LP16-ESCA (OS)

Kaplan–Meier survival curve for MTND4LP16 RNA expression in ESCA: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with MTND4LP16 in patient tissues and cancer cell lines. In patient samples, MTND4LP16 shows the broadest associations at the RNA and protein expression levels, with COAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	6,758	COAD (3020)	view →
Function (RNA)	4,814	STAD (4512)	view →