MTND4LP1

Across TCGA pan-cancer cohorts, MTND4LP1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of MTND4LP1’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where MTND4LP1 RNA is repressed in tumor relative to normal tissue. In most cancer types MTND4LP1 is over-expressed in tumor, although a few such as UCEC and COAD show the opposite, repressed pattern.

UCEC, COAD, and ESCA are the cancer types where MTND4LP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTND4LP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	III,IV	−0.367	.040	2	view →
COAD	All	III,IV	−0.242	.008	2	view →
ESCA	All	All	−0.893	.022	1	view →
KICH	All	All	+0.254	.025	1	view →
KIRC	Female	All	−0.179	.022	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

MTND4LP1–UCEC

Open the UCEC breakdown →