MTND3P6

Across TCGA patient cohorts, MTND3P6 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,103 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MTND3P6-associated GO terms across cancer lineages are Regulation of double-strand break repair, Positive regulation of double-strand break repair, and ERAD pathway. Each is linked with MTND3P6 in more than 5 cancer types. Because this analysis shows association rather than direction, both MTND3P6-to-partner and partner-to-MTND3P6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of double-strand break repair grouped by MTND3P6-low versus MTND3P6-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTND3P6→partner) and Y-score (partner→MTND3P6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of double-strand break repair →	+0.101	+0.133	<.001	.003	3	6
ESCA	Positive regulation of double-strand break repair →	+0.103	+0.072	<.001	.004	3	6
ESCA	ERAD pathway →	+0.115	+0.114	<.001	.002	3	6
STAD	Mitochondrial fusion →	+0.093	+0.049	<.001	<.001	3	6
STAD	Protein localization to cilium →	+0.060	+0.051	<.001	<.001	3	6
ESCA	Morphogenesis of embryonic epithelium →	+0.094	+0.106	<.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,103 associations by consensus.

Regulation of double-strand break repair by MTND3P6 expression — ESCA

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