Q-omics provides the consensus-scored MTND3P5 profile across patient tissues and cancer cell-line models. MTND3P5 expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in READ. Among the 18 cancer types available for tumor–normal comparison, MTND3P5 is differentially expressed in 3, with the highest sampling consensus in READ. Additionally, MTND3P5 RNA expression shows 7,607 significant gene co-expression associations, with the highest sampling consensus in ESCA. Together, these results highlight READ, and ESCA as cancer lineages where MTND3P5 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MTND3P5 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MTND3P5 survival associations across molecular data types. MTND3P5 RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MTND3P5 RNA expression–survival associations across cancer types. High MTND3P5 expression shows unfavorable associations in READ, UCS, BLCA, THYM, MESO and LAML. The READ Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify READ as the clearest survival context for MTND3P5 RNA expression.
This table summarizes MTND3P5 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in READ for RNA.
This table ranks reproducible tumor–normal expression differences for MTND3P5. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MTND3P5 shows lower tumor expression in READ and higher tumor expression in KIRC and THCA. The READ box plot shows higher MTND3P5 RNA expression in normal versus tumor tissue (log2 FC = −0.240, t-test p = .026).
This table shows molecular features associated with MTND3P5 in patient tissues and cancer cell lines. In patient samples, MTND3P5 shows the broadest associations at the RNA and protein expression levels, with ESCA recurring as the lineage with the largest associated feature set.
