Across TCGA pan-cancer cohorts, MTND3P21 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of MTND3P21’s most consistent transcriptional readouts.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where MTND3P21 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MTND3P21 is over-expressed in tumor.
LIHC are the cancer types where MTND3P21 tumor–normal differential expression is most reproducible.