MTND3P12

Across TCGA pan-cancer cohorts, MTND3P12 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MTND3P12’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where MTND3P12 RNA is repressed in tumor relative to normal tissue. In most cancer types MTND3P12 is over-expressed in tumor, although a few such as LUSC and KICH show the opposite, repressed pattern.

LUSC and KICH are the cancer types where MTND3P12 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTND3P12 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	−0.050	.006	2	view →
KICH	All	All	−0.032	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

MTND3P12–LUSC

Open the LUSC breakdown →