Across TCGA pan-cancer cohorts, MTND3P1 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of MTND3P1’s most consistent transcriptional readouts.
The strongest signal is observed in esophageal carcinoma (ESCA), where MTND3P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MTND3P1 is over-expressed in tumor.
ESCA are the cancer types where MTND3P1 tumor–normal differential expression is most reproducible.