MTND2P8

Across TCGA pan-cancer cohorts, MTND2P8 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MTND2P8’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where MTND2P8 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MTND2P8 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

KICH, LIHC, and KIRC are the cancer types where MTND2P8 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTND2P8 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	+0.014	.025	2	view →
LIHC	Male	All	+0.009	.041	1	view →
KIRC	Male	II,III,IV	−0.009	.027	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

MTND2P8–KICH

Open the KICH breakdown →