MTND2P2

Across TCGA pan-cancer cohorts, MTND2P2 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated MTND2P2 data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher MTND2P2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MTND2P2 expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

DLBC, LUSC, and UCS are the cancer types where MTND2P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	OS	Tertile	III,IV	0.172	0.907	<.001	63	view →
LUSC	OS	Tertile	IV	0.001	0.673	.014	36	view →
UCS	DFS	Tertile	IV	0.132	0.718	.002	36	view →
TGCT	DFS	Tertile	II,III,IV	0.523	0.952	.006	36	view →
KICH	DFS	Quartile	III,IV	0.042	0.774	<.001	27	view →
ACC	DFS	Tertile	II,III,IV	0.202	0.618	.006	27	view →
LGG	DFS	Tertile	All	0.220	0.476	.001	18	view →
UVM	OS	Tertile	III,IV	0.220	0.811	.021	18	view →
UCEC	DFS	Tertile	IV	0.219	0.550	.032	12	view →
ESCA	DFS	Tertile	III,IV	0.457	0.273	.020	10	view →
THYM	OS	Tertile	II,III,IV	0.395	0.862	.047	6	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

MTND2P2–DLBC (OS)

Open the DLBC breakdown →